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In a statement to Insider, Novo Nordisk, the company that makes Wegovy and Ozempic, said that Gila monsters and the discovery of exendin-4 "did not have anything to do with our decision to develop long-acting GLP-1 receptor agonists" for obesity, because "that was based on GLP-1 biology in humans." But the company also said that "the GLP-1-like effect of exendin-4" in Gila monsters was "an important contribution to the field," as it led to the development of the very first injectable drug of its kind

The practical longevity implications require long-term supplementation and are not assessable on short cycle timescales

The ideal candidate is someone seeking a clearer, brighter, and more even complexion without opting for invasive or chemical-heavy procedures

J Biol Chem 293:6259

DAsta, A